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FOXO4-DRI 5mg

FOXO4-DRI 5mg

$225.00

Out of stock

FOXO4-DRI is a synthetic peptide designed to disrupt the interaction between the FOXO4 transcription factor and p53 protein. This disruption has been researched for its potential to selectively induce apoptosis in senescent cells, thereby contributing to studies on aging and age-related diseases.

Important Information About This Research Product:

  • Your vials are not empty; the product is at the bottom of the vial.
  • All peptides are provided in lyophilized (freeze-dried) powder form and must be reconstituted with bacteriostatic water (not provided).
  • Store in a cool, dry, dark place, away from UV rays. For best preservation, store at ≤ 4°C.
  • This product is intended for laboratory and research use only. No instructions on reconstitution or dosing can be provided.

Appearance

Lyophilized Powder

Synonyms

FOXO4-D-Retro-Inverso Peptide, Proxofim

CAS #

2095472-65-0

Molecular Formula

C152H252N44O42S

Molecular Weight

3361.96 g/mol

Storage

Store all products in a dry, cool, and dark place away from UV rays. For best preservation, store at 4°C.

Description

FOXO4-DRI is a cell-penetrating peptide that mimics a segment of the FOXO4 protein, enabling it to interfere with the FOXO4-p53 interaction. By disrupting this interaction, FOXO4-DRI facilitates the relocation of p53 from the nucleus to the cytoplasm in senescent cells, leading to the activation of apoptotic pathways. This mechanism has been explored in research focusing on the elimination of senescent cells to potentially mitigate the effects of aging and improve tissue homeostasis. Studies have investigated its role in alleviating age-related conditions and enhancing regenerative capacities in various tissues.